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I had to deal with this.. Was friends with her for a few years, but never saw this side of her until a while after we started dating. It was like everything was normal and after 20 hours, instead of unlocking Mewtwo, I unlocked this alternate personality for my girlfriend where she's crazier than the fucking Joker.
You will feel bad, but there's no clean way to do it. If you do it in person, she'll probably try to attack you, or your car.
I know how dickheaded it is, but girls with problems will not let you leave if you do it in person. You have to tell yourself you don't deserve to be a caretaker your entire life. It's sad, but you have a right to your own life. Say something online or over the phone and cut off contact.
And watch the fuck out. If she knows where you live, she'll at least THINK of doing some crazy shit.