>>2988968Talking to yourself is a sign of being crazy, which Misato assumes he is.
He's actually pretty bad at hiding it, he hums to himself which even Anno remarks saying is psycho-like behavior and has no idea how to strike a conversation as he even makes Rei uncomfortable.
If not psycho, he definitely gave off the impression of autism to others.
But Kaworu is rather fucked up, he's the most suicidal person in the whole show after all.